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®
                       AP  Science Practice           Check Your Understanding

                    Examine the Concept                                 Apply the Concept
                    ▶ ▶Explain how a stimulant affects behavior.        ▶ ▶Think of a friend or family member who is addicted to
                    ▶ ▶Explain the physiological effects of nicotine.   nicotine. What do you think would be most effective to say to
                    ▶ ▶Explain the withdrawal symptoms someone should expect   that person to convince them to try to quit?
                    when quitting smoking.
                    Answers to the Examine the Concept questions can be found in Appendix C at the end of the book.

                         molecule Distributed by Bedford, Freeman & Worth Publishers. Not for redistribution.



                                                Cocaine
                      ®
                   AP  Exam Tip
                                                Cocaine is a powerfully addictive stimulant derived from the coca plant. The recipe for
                   Figure 1.3-9 is an excellent review   Coca-Cola originally included a coca extract, creating a mild cocaine tonic intended for
                   of how neurotransmitters work. If   tired elderly people. Between 1896 and 1905, Coke was indeed “the real thing.” Today,
                   there is any part of this figure that   cocaine is snorted, injected, or smoked (sometimes as crack cocaine, a faster-working crys-
                   you don’t understand, head back   tallized form that produces a briefer but more intense high, followed by a more intense
                   to the beginning of Module 1.3 for
                   a complete explanation.      crash). Cocaine enters the bloodstream quickly, producing a rush of euphoria that depletes
                                                the brain’s supply of the neurotransmitters dopamine, serotonin, and norepinephrine
                                                (Figure 1.3-9). Within the hour, a crash of agitated depression follows as the drug’s effect
                                                wears off. After several hours, the craving for more wanes, only to return several days later
                                                (Gawin, 1991).
                                                   In situations that trigger aggression, ingesting cocaine may heighten reactions. Caged
                   Figure 1.3-9            Copyright © Bedford, Freeman & Worth Publishers.
                                                rats fight when given foot shocks, and they fight even more when given cocaine and foot
                   Cocaine euphoria and crash



                                               Sending
                                               neuron

                                                 Action
                                                 potential


                                                                                  Reuptake
                 Synaptic gap




                 Receiving neuron

                    Neurotransmitter                                                                               Cocaine
                                             Receptor
                                             sites
                                       (a)                               (b)                              (c)
                         Neurotransmitters carry a message from a   The sending neuron normally reabsorbs   By binding to the sites that normally reabsorb
                         sending neuron across a synapse to receptor   excess neurotransmitter molecules, a   neurotransmitter molecules, cocaine blocks
                         sites on a receiving neuron.       process called reuptake.        reuptake of dopamine, norepinephrine, and
                                                                                            serotonin (Ray & Ksir, 1990). The extra
                                                                                            neurotransmitter molecules therefore remain
                                                                                            in the synapse, intensifying their normal mood-
                                                                                            altering effects and producing a euphoric rush.
                                                                                            When the cocaine level drops, the absence of
                                                                                            these neurotransmitters produces a crash.


                 48   Unit 1  Biological Bases of Behavior






          03_myersAPpsychology4e_28116_ch01_002_163.indd   48                                                                   15/12/23   9:22 AM
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