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3.   The two strands in a double helix of DNA are

                                                                                                                        ®
                       (A)   parallel.                                     Module 5                             PREP FOR THE AP  EXAM
                                                                             ®
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                       (B)   complementary.                             AP    Practice Questions
                       (C)   held together by covalent bonds.
                       (D)   held together by ionic bonds.                 Section 1: Multiple-Choice Questions

                       4.   The linkage between nucleotides is referred to       Choose the best answer for questions 1–4.

                    as a(n)                                                 1.    Which is true of nucleic acids and proteins?
                       (A)   ionic bond.                                          (A)  The subunits of nucleic acids are nucleotides, and

                       (B)   peptide bond.                                     the subunits of proteins are sugars.

                       (C)   phosphodiester bond.                                 (B)  Nucleic acids and proteins are formed when their
                       (D)   glycosidic bond.                                  subunits join together with phosphodiester bonds.
                                                                               (C)   Dehydration synthesis reactions are necessary to
                    5.    Which represents a standard base pair interaction?     produce nucleic acids, while hydrolysis reactions are
                       (A)   G–C                                               necessary to produce proteins.
                       (B)   G–T                                               (D)   Nucleic acids carry genetic information, while
                       (C)   C–A                                                 proteins provide structure and do much of the
                       (D)   A–G                                               work of the cell.

                       6.   An organism’s genome is analyzed and found to      2.    Which is an example of a nucleotide?

                      contain 18% thymine. What percentage of that             (A)   Adenine–ribose–a carboxyl group
                     organism’s DNA is cytosine?                               (B)   Guanine–deoxyribose–a phosphate group
                       (A)   18%                                               (C)   Uracil–deoxyribose–a phosphate group
                       (B)   32%                                               (D)   Thymine–ribose–a carboxyl group
                       (C)   36%

                       (D)   82%                                              3.   One strand of DNA has the sequence 5′-GTGCA-3′.
                                                                            What is the 5′ → 3′ sequence of the complementary
                    7.    Ribose differs from deoxyribose in that a         DNA strand?
                       (A)   ribose has an extra hydroxyl group.               (A)   CACGT
                       (B)   ribose is missing a hydroxyl group.               (B)   TGCAC
                       (C)   ribose has an extra phosphate group.              (C)   UGCAC
                       (D)   ribose is missing a phosphate group.              (D)   CACGU
                    8.    The base uracil pairs with                          4.   Which is a shared structural trait of DNA and RNA?

                       (A)   adenine.                                          (A)      ′ → ′ 3  directionality
                                                                               5


                       (B)   thymine.                                          (B)   A hydroxyl group at the 2′ carbon
                       (C)   guanine.                                          (C)   Base pairing of adenine and thymine
                       (D)   cytosine.                                         (D)   The double helical shape



















                 86   UNIT 1  cHeMisTRY OF liFe

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